FACTORS ASSOCIATED WITH SURVIVAL IN KIDNEY TRANSPLANTATION 410 100

A REVIEW OF THE LITERATURE

Authors

DOI:

https://doi.org/10.56579/rei.v8i1.1859

Keywords:

Kidney Transplantation, survival, Donor Selection, Chronic Kidney Failure

Abstract

Renal Transplantation is a kind of therapy that is adopted for patients on end-stage chronic kidney disease with more cost-effectivity than others replacement therapy. There are many factors that can influence patient and graft survival. The objective of this study was to identify factors associated with the survival of patients and organs in adults undergoing kidney transplantation. A review was conducted using the Virtual Health Library database, which allowed searches in databases such as Lilacs and PubMed. A total of 208 articles were identified, of which 18 were selected. Among the most analyzed factors associated with patient survival are those related to the donor, recipient, and care aspects concerning dialysis and transplantation. Regarding the donor, it was observed that living donors, male sex, and younger age are associated with higher survival rates. As for the recipient, underlying conditions such as diabetes, a previous cancer diagnosis, infections by cytomegalovirus (CMV), and female sex are associated with higher survival. Regarding immunological aspects, greater compatibility was associated with higher survival. Care-related factors, such as having private health insurance and shorter cold ischemia time, were also associated with higher survival. It is concluded that different factors are associated with kidney graft survival. Among these, the most frequently described in the literature are those related to the donor, recipient, and post-transplant renal function. However, these factors must always be evaluated comprehensively.

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Author Biographies

  • Pollyanna Barbosa Farias Barros, University of Brasília

    Doctoral candidate in the Graduate Program in Health Sciences and Technologies at the Faculty of Ceilândia, University of Brasília (FCE-UnB). Member of the Kidney Transplant Research Group at the University Hospital of Brasília (HuB). Holds a Master’s degree in Biosciences Applied to Pharmacy from the Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (FCFRP-USP), and a Bachelor’s degree in Pharmacy-Biochemistry from the Federal University of Maranhão (UFMA). Associate Professor in the Medicine program at the University of Rio Verde, Formosa campus, Goiás. Ombudsperson at the UNIEURO University Center, Federal District.

  • Davi Peixoto de Freitas, University of Brasília

    Pharmacy Student at the University of Brasília – Ceilândia Campus. Brazil, Federal District, Brasília.

  • Mariana Magalhães Maranhão, University of Brasília

    Pharmacy Student at the University of Brasília – Ceilândia Campus. Brazil, Federal District, Brasília.

  • Gabriel Cesar Resende, University of Brasília

    Pharmacy Student at the University of Brasília – Ceilândia Campus. Brazil, Federal District, Brasília.

  • Geraldo Rubens Ramos de Freitas, University of Brasília

    Nephrologist, Doctor in Nephrology, Transplant Unit of the University Hospital of Brasília. Brazil, Federal District, Brasília.

  • Dayani Galato, University of Brasília

    Pharmacist, PhD, Professor of the Pharmacy Program, the Graduate Program in Health Sciences and Technologies (PGCTS), and the Graduate Program in Pharmaceutical Assistance (PPGCTS) at the University of Brasília – Ceilândia Campus. Brazil, Federal District, Brasília.

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FACTORS ASSOCIATED WITH SURVIVAL IN KIDNEY TRANSPLANTATION: A REVIEW OF THE LITERATURE. (2026). Interdisciplinary Studies Journal, 8(1), 01-25. https://doi.org/10.56579/rei.v8i1.1859