FACTORS ASSOCIATED WITH SURVIVAL IN KIDNEY TRANSPLANTATION
A REVIEW OF THE LITERATURE
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https://doi.org/10.56579/rei.v8i1.1859Keywords:
Kidney Transplantation, survival, Donor Selection, Chronic Kidney FailureAbstract
Renal Transplantation is a kind of therapy that is adopted for patients on end-stage chronic kidney disease with more cost-effectivity than others replacement therapy. There are many factors that can influence patient and graft survival. The objective of this study was to identify factors associated with the survival of patients and organs in adults undergoing kidney transplantation. A review was conducted using the Virtual Health Library database, which allowed searches in databases such as Lilacs and PubMed. A total of 208 articles were identified, of which 18 were selected. Among the most analyzed factors associated with patient survival are those related to the donor, recipient, and care aspects concerning dialysis and transplantation. Regarding the donor, it was observed that living donors, male sex, and younger age are associated with higher survival rates. As for the recipient, underlying conditions such as diabetes, a previous cancer diagnosis, infections by cytomegalovirus (CMV), and female sex are associated with higher survival. Regarding immunological aspects, greater compatibility was associated with higher survival. Care-related factors, such as having private health insurance and shorter cold ischemia time, were also associated with higher survival. It is concluded that different factors are associated with kidney graft survival. Among these, the most frequently described in the literature are those related to the donor, recipient, and post-transplant renal function. However, these factors must always be evaluated comprehensively.
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