INTERVENCIONES LIDERADAS POR FARMACÉUTICOS PARA LA PROFILAXIS RACIONAL DE LA ENFERMEDAD MUCOSA RELACIONADA CON EL ESTRÉS EN UCI:
UNA REVISIÓN INTEGRATIVA
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https://doi.org/10.56579/rei.v7i4.1689Palabras clave:
Terapia Intensiva, Deprescripción, Seguridad del Paciente, Farmacia Clínica, Lesión de la Mucosa Relacionada con el EstrésResumen
Las intervenciones farmacéuticas mejoran los resultados clínicos en la profilaxis de la lesión mucosa relacionada con el estrés (LMRE) en unidades de cuidados intensivos (UCI) y reducen los costos hospitalarios. Esta revisión identifica estrategias de farmacéuticos para reducir el uso inapropiado de inhibidores de la bomba de protones (IBP) en la profilaxis de la lesión aguda de la mucosa gástrica (LAMG) en pacientes de UCI. Se realizó una revisión integrativa en bases de datos como BVS, LILACS, PubMed (MEDLINE), SciELO, Cochrane Library y Google Scholar, con foco en estudios de los últimos 5 años (hasta noviembre de 2022). Se utilizó un enfoque descriptivo para analizar las intervenciones farmacéuticas y sus resultados. De los 204 registros identificados, 9 artículos cumplieron con los criterios de inclusión. Intervenciones como guías y protocolos aumentaron la eficacia clínica de la profilaxis de LMRE en UCI, asegurando prescripciones adecuadas y adhesión a las directrices. Estas estrategias también redujeron significativamente los costos mensuales y anuales. La participación de farmacéuticos clínicos en el desarrollo de guías de profilaxis de LMRE y en discusiones multidisciplinarias se mostró como la estrategia más eficaz para mejorar los resultados. Sin embargo, se necesitan más estudios para evaluar la relación costo-efectividad de estas intervenciones.
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