CLINICAL AND FUNCTIONAL PROFILE ANALYSIS OF MECHANICALLY VENTILATED PATIENTS IN THE INTENSIVE CARE UNIT
Visualizações: 152DOI:
https://doi.org/10.56579/rei.v8i3.3111Keywords:
; Hospitalization;Abstract
Mechanical ventilation is frequently required in critically ill patients with respiratory failure; however, it is associated with the development of Intensive Care Unit–Acquired Weakness (ICU-AW) and significant functional impairments resulting from prolonged immobilization, which may persist for years after hospital discharge. This study aimed to compare functional capacity and muscle strength in patients undergoing mechanical ventilation at the time of ICU discharge, considering the duration of ventilatory support. This retrospective study was conducted through the analysis of electronic medical records of patients admitted to an Intensive Care Unit. Mobility was assessed using the Intensive Care Unit Mobility Scale (IMS), which classifies functional status from bed rest to independent ambulation, while global muscle strength was measured using the Medical Research Council (MRC) scale, based on the grading of specific upper and lower limb muscle groups. A total of 362 patients were analyzed and divided into three groups according to the duration of mechanical ventilation. Longer ventilation times were associated with lower IMS and MRC scores, as well as greater clinical severity. In conclusion, prolonged mechanical ventilation negatively impacts mobility and muscle strength, with mobility emerging as the most sensitive and earliest affected functional marker.
Keywords: Early Mobilization; Post-Intensive Care Syndrome; Mechanical Ventilation.
Downloads
References
AQUIM, E. E. et al. Brazilian guidelines for early mobilization in intensive care unit. Revista Brasileira de Terapia Intensiva, v. 31, n. 4, 2019. Disponível em: https://pubmed.ncbi.nlm.nih.gov/31967216/. Acesso em: 30 set. 2024. DOI: https://doi.org/10.5935/0103-507X.20190084
BARCELLOS, Ruy de Almeida; CHATKIN, José Miguel. Impact of a multidisciplinary checklist on the duration of invasive mechanical ventilation and length of ICU stay. Jornal Brasileiro de Pneumologia, v. 46, n. 3, p. e20180261, 2020. Disponível em: https://www.jornaldepneumologia.com.br/details/3322/en-US/impact-of-a-multidisciplinary-checklist-on-the-duration-of-invasive-mechanical-ventilation-and-length-of-icu-stay. Acesso em: 22 ago. 2025. DOI: https://doi.org/10.36416/1806-3756/e20180261
BÉDUNEAU, Gaëtan et al. Epidemiology of weaning outcome according to a new definition: the WIND study. American Journal of Respiratory and Critical Care Medicine, v. 195, n. 6, p. 772–783, 2017. Disponível em: https://pubmed.ncbi.nlm.nih.gov/27626706/. Acesso em: 2 set. 2025. DOI: https://doi.org/10.1164/rccm.201602-0320OC
CANELHAS, M. et al. Impact of mechanical ventilation time on functional capacity and muscular strength of patients under intensive care. Fisioterapia em Movimento, v. 35, p. e35125, 2022. Disponível em: https://www.scielo.br/j/fm/a/RGDmmBH4Kcw44NRfHbjpjzb/. Acesso em: 25 set. 2024. DOI: https://doi.org/10.1590/fm.2022.35125
CASTRO, L. A. et al. Desmame da ventilação mecânica em pacientes com COVID-19. ASSOBRAFIR Ciência, v. 11, supl. 1, p. 175–182, 2020. Disponível em: https://bjr-assobrafir.org/journal/assobrafir/article/doi/10.47066/2177-9333.AC20.covid19.017. Acesso em: 29 set. 2024. DOI: https://doi.org/10.47066/2177-9333.AC20.covid19.017
GOULART FILHO, F. A. et al. Análise do processo de desmame da ventilação mecânica na unidade de terapia intensiva de um hospital da zona da mata mineira. HuRevista, v. 50, n. 2, p. 1–10, 2025. Disponível em: https://periodicos.ufjf.br/index.php/hurevista/article/view/48209. Acesso em: 20 ago. 2025.
HISER, Stephanie L. et al. Intensive care unit acquired weakness and physical rehabilitation in the ICU. BMJ, p. e077292, 2025. Disponível em: https://pubmed.ncbi.nlm.nih.gov/39870417/. Acesso em: 21 ago. 2025. DOI: https://doi.org/10.1136/bmj-2023-077292
LIDIA, Bertha et al. Efecto de una rehabilitación temprana en pacientes con debilidad adquirida en la Unidad de Cuidados Intensivos. Medicina Crítica, v. 36, n. 1, p. 39–44, 2022. Disponível em: https://www.scielo.org.mx/scielo.php?pid=S2448-89092022000100039. Acesso em: 20 ago. 2025. DOI: https://doi.org/10.35366/104474
MACHADO, J. et al. Bundles do combate à fraqueza adquirida na unidade de terapia intensiva. Braspen Journal, v. 36, n. 2, p. 131–144, 2021. Disponível em: https://braspenjournal.org/journal/braspen/article/doi/10.37111/braspenj.2021.36.2.01. Acesso em: 30 set. 2024. DOI: https://doi.org/10.37111/braspenj.2021.36.2.01
MUNIR, Misbakul; MELASTUTI, Erna; ABDURROUF, Muh. Early mobilization for ICU-acquired weakness in the critically ill on a ventilator. Indonesian Journal of Global Health Research, v. 7, n. 2, p. 867–874, 2025. Disponível em: https://www.researchgate.net/publication/392087634. Acesso em: 21 ago. 2025. DOI: https://doi.org/10.37287/ijghr.v7i2.5800
MUSUMECI, R. et al. Preditores de desmame prolongado da ventilação mecânica em pacientes com COVID-19 em unidade de terapia intensiva. Jornal Brasileiro de Pneumologia, p. e20230131, 2023. Disponível em: https://www.jbp.org.br/statistics/3870/pt-BR. Acesso em: 20 ago. 2025.
NICOLAU, Nicácio et al. Fatores associados à maior mortalidade em unidades de terapia intensiva no Brasil. Brazilian Journal of Implantology and Health Sciences, v. 7, n. 1, p. 1736–1747, 2025. Disponível em: https://bjihs.emnuvens.com.br/bjihs/article/view/4979. Acesso em: 24 ago. 2025. DOI: https://doi.org/10.36557/2674-8169.2025v7n1p1736-1747
OLIVEIRA, Gessica Rodrigues de et al. Barreiras enfrentadas por fisioterapeutas para realizar a mobilização precoce em unidades de terapia intensiva. ASSOBRAFIR Ciência, v. 14, p. e46327, 2023. Disponível em: https://bjr-assobrafir.org/journal/assobrafir/article/doi/10.47066/2177-9333.AC.2022.0054. Acesso em: 10 ago. 2024. DOI: https://doi.org/10.47066/2177-9333.AC.2022.0054
OPPELT, L. L. et al. Taxa de descontinuação de ventilação mecânica em pacientes com COVID-19: um estudo observacional multicêntrico. Fisioterapia Brasil, v. 25, n. 5, p. 1715–1724, 2024. Disponível em: https://ojs.atlanticaeditora.com.br/index.php/fisioterapia-brasil/article/view/312. Acesso em: 20 ago. 2025. DOI: https://doi.org/10.62827/fb.v25i5.1024
PAULO, F. V. dos S. et al. Mobilização precoce: a prática do fisioterapeuta intensivista – intervenções e barreiras. Revista Pesquisa em Fisioterapia, v. 11, n. 2, p. 298–306, 2021. Disponível em: https://www5.bahiana.edu.br/index.php/fisioterapia/article/view/3586. Acesso em: 20 set. 2024. DOI: https://doi.org/10.17267/2238-2704rpf.v11i2.3586
RANZANI, Angélica Félix; SOUZA, Marcela Hilário de; FERREIRA, Lucas Lima. Comparação de desfechos clínicos e correlação entre funcionalidade e tempo de ventilação mecânica de pacientes em UTI. Arquivos de Ciências da Saúde da UNIPAR, v. 26, n. 3, 2022. Disponível em: https://revistas.unipar.br/index.php/saude/article/view/8827. Acesso em: 24 ago. 2025. DOI: https://doi.org/10.25110/arqsaude.v26i3.2022.8827
RENNER, C. et al. Guideline on multimodal rehabilitation for patients with post-intensive care syndrome. Critical Care, v. 27, n. 1, 2023. Disponível em: https://pubmed.ncbi.nlm.nih.gov/37525219/. Acesso em: 25 set. 2024. DOI: https://doi.org/10.1186/s13054-023-04569-5
SCHMIDT, D. et al. Post–COVID-19 intensive care unit-acquired weakness compromises long-term functional status. Physical Therapy, v. 103, n. 12, 2023. Disponível em: https://pubmed.ncbi.nlm.nih.gov/37658771/. Acesso em: 10 ago. 2024. DOI: https://doi.org/10.1093/ptj/pzad117
SOUSA, A. C. M.; SANCHEZ, L. C. A.; FERREIRA, L. L. Desfechos clínicos de pacientes submetidos à ventilação mecânica invasiva em uma UTI neurocirúrgica. ASSOBRAFIR Ciência, v. 12, p. e42286, 2021. Disponível em: https://www.bjr-assobrafir.org/doi/10.47066/2177-9333.AC.2020.0021. Acesso em: 24 ago. 2025. DOI: https://doi.org/10.47066/2177-9333.AC.2020.0021
WERLANG, Alessandra Preisig et al. Clinical outcomes of intensive care unit-acquired weakness in critically ill COVID-19 patients: a prospective cohort study. Critical Care Science, v. 36, 2024. Disponível em: https://www.scielo.br/j/ccsci/a/RssQpMnwVzMkKq7qDmNMJ5q/. Acesso em: 20 ago. 2025.
XU, Y. et al. Impact of pressure support ventilation duration after a spontaneous breathing trial on reintubation rates in critically ill subjects: a retrospective study. BMC Pulmonary Medicine, v. 25, n. 1, 2025. Disponível em: https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-025-03744-4. Acesso em: 20 ago. 2025. DOI: https://doi.org/10.1186/s12890-025-03744-4
ZHOU, Jing et al. Effect of early progressive mobilization on intensive care unit-acquired weakness in mechanically ventilated patients: an observational study. Medicine, v. 101, n. 44, p. e31528, 2022. Disponível em: https://journals.lww.com/md-journal/fulltext/2022/11040/effect_of_early_progressive_mobilization_on.62.aspx. Acesso em: 2 set. 2025. DOI: https://doi.org/10.1097/MD.0000000000031528
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Interdisciplinary Studies Journal
This work is licensed under a Creative Commons Attribution 4.0 International License.
The Journal of Interdisciplinary Studies adopts the Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows for sharing and adapting the work, including for commercial purposes, provided proper attribution is given and the original publication in this journal is acknowledged.
The Creative Commons 4.0 International license allows authors to share their works with flexibility, ensuring copyright while permitting specific uses such as reproduction, distribution, and adaptation, provided that the conditions are met, such as giving credit to the original author.